Endocrinology and Methabolism Diseases

Auxologico can boast excellence in the field of Endocrinology and Metabolism Diseases because, since its foundation, it has carried out a wide and well-organized clinical and scientific activity.

Most Operational Units managed under the direction of the University, several national and international scientific collaborations and the development and implementation of multidisciplinary diagnostic and therapeutic pathways for the treatment of complex endocrine and metabolic diseases make Auxologico an acknowledged point of reference in this field.

The main activities refer to the prevention, diagnosis and treatment of hormonal disorders and metabolism diseases, fertility disorders, nutrition and growth disorders, thyroid diseases.

Auxologico boasts specific expertise in the field of severe obesity in adults and minors, including Eating Disorders, diabetes, osteoporosis, thyroid diseases and rare endocrine diseases.
Highly specialized centers are dedicated to these diseases.

These activities are carried out in outpatient clinics, in Day Hospitals, MACs, and as inpatient treatments.

ACCESS TO SERVICES

Both national (Servizio Sanitario Nazionale) and private health insurance schemes entitle people to access the services and treatments provided.

CLINICAL ACTIVITY

Endocrine diseases

  1. Thyroid, parathyroid and adrenal diseases.
  2. Hypogonadism, Primary Ovarian Insufficiency
  3. Growth deficiency/Pubertal delay, Kallmann Syndrome/ hypopituitarism.
  4. Pituitary tumours.
  5. Hereditary Endocrine Tumours (MEN 1/MEN2/Medullary Thyroid Cancer /FIPA/pheochromocytomas and paragangliomas).

Obesity and diabetes

  1. Eating disorders (anorexia and bulimia).
  2. Adult and childhood obesity.
  3. Autoimmune and non-autoimmune diabetes mellitus.

Bone Metabolism

  1. Idiopathic, secondary and postmenopausal osteoporosis.
  2. Bone metabolism disorders in children and in kidney failure.
  3. Paget's disease of bone.
  4. Osteomalacias, deficiency and genetic rickets.

INNOVATIVE TECNIQUES

  1. Percutaneous ethanol injection for cystic thyroid nodules.
  2. Genetic analysis with the Next Generation Sequencing.
  3. 3 Tesla Magnetic Resonance Imaging (MRI 3T) for early diagnosis of neuroendocrine lesions.
  4. Software for height-weight growth pattern analysis.
  5. Air Plethysmography.
  6. Multidisciplinary outpatient clinic for Thyroid-Associated Ophthalmopathy (in collaboration with Neuro-ophthalmology).
  7. Multidisciplinary rehabilitation for obesity and eating disorders.
  8. Frequency Rhythmic Electrical Modulation System for the treatment of neuropathies and diabetic ulcers.
  9. Molecular diagnosis of genetic bone diseases.
  10. Evaluation of intestinal calcium absorption by cold tracer.
  11. Bone biopsy with quantitative histomorphometric evaluation.

RESEARCH TOPICS

  1. Development of new therapies for resistant endocrine neoplasias, osteoporosis and diabetes.
  2. Study of genetic and epigenetic causal mechanisms of thyroid diseases, pubertal defects and early menopause.
  3. Studies on genotypic and phenotypic variants of osteogenesis imperfecta.
  4. Genetic obesity.
  5. Transcriptome of human adipose deposits with microarray technologies (gene expression, methylation, Genome Wide Association studies).
  6. Database for growth syndrome and rare diseases.

INTERNATIONAL COLLABORATION AND REFERENCE CENTRES

  1. Dept. of Endocrinology, Erasmus University, Rotterdam, NL.
  2. Dept. of Endocrinology and Metabolism, University of Cambridge, UK.
  3. COST action of the EC (code BM1105: GnRH network).
  4. Dept. of Pediatrics/Genetics, University of Chicago, USA.
  5. Genetics Unit, Shriners Hospital for Children and McGill University, Montréal, Québec, Canada.
  6. Dept. of Endocrinology, Boston Children's Hospital, Harvard Medical School, USA.
  7. Dept. of Bone Diseases, Faculty of Medicine, Geneva University Hospital, Geneva, CH.
  8. Department of Youth Health Care, Katholieke Universiteit Leuven, Belgium.
  9. Department of Nutrition, Federal University of Sao Paulo, Brazil.
  10. Section of Child Life and Health, University of Edinburgh, UK.
  11. Section for Pediatrics, Department of Clinical Medicine, University of Bergen, Norway.
  12. Laboratoire d’Histodynamique Osseuse, Faculté de Médecine Laennec, Lyon, France.